UM = ultrarapid metabolizer, EM = extensive metabolizer, IM = intermediate metabolizer, PM = poor metabolizer Drug SNP Types Effect Race Misc Ivacaftor CFTR amitriptyline CYP 2C19 UM (R), EM, IM, PM PM = increased conc, side effects, UM = decreased concen PM =Common in Asians UM=Common in Caucasions […]
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Sleep Disturbances
Lifestyle Modifications: Maintain sleep schedule Do not go to bed unless tired Sleep long enough, but not too much Optimize bedroom lighting, temp and sound Develop a ritual Do not stay in bed for more than 15 minutes if you can’t sleep Don’t go to bed hungry. Only use the bedroom for sleep Avoid naps Avoid […]