UM = ultrarapid metabolizer, EM = extensive metabolizer, IM = intermediate metabolizer, PM = poor metabolizer Drug SNP Types Effect Race Misc Ivacaftor CFTR amitriptyline CYP 2C19 UM (R), EM, IM, PM PM = increased conc, side effects, UM = decreased concen PM =Common in Asians UM=Common in Caucasions […]