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Digital PharmD

Informatics in Pharmacy

Fluids

August 12, 2018 By Dr. G, PharmD

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IV FluidInfused VolumeIntervascular Volume ExpansionFluid Type
Normal Saline1000 ml250 mlcrystalloid
Lactated Ringers1000 ml250 mlcrystalloid
Normosol and Plasmalyte1000 ml250 mlcrystalloid
D5W1000 ml100 mlcrystalloid
Albumin 5%500 ml500 mlcolloid
Albumin 25%100 ml500 mlcolloid
Hydroxyethyl Starch500 ml500 mlcolloid

Signs of volume depletion:

  • Tachycardia >100 bpm, hypotension, SBP < 80, orthostatic changes, increase BUN:SCr ratio >20:1, dry mucous membranes, decreased skin turgor, reduced urine output, dizziness and improvement in HR and BP after 500-1000 ml fluid bolus.
  • Crystalloids are recommended in volume depletion, colloids are not.

Filed Under: Fluid, Electrolytes, & Nutrition

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acid base acidosis acute coronary syndrome alkalosis analgesics anaphylaxis aortic dissection arrhythmia Beta-Blockers biostatistics blood pressure cardiac markers CHA2DS2-VasC cocaine COVID-19 diabetes diabetes inspidius Guidelines heart failure Heparin hypersensitivity hypertension hypovolemic shock intubation ionotropes journal club lipids LMWH medication safety morphine conversions myocardial infarction needs work NOAC NSTEMI obstructive shock pharmacoeconomics pheochromocytoma pressors reference materials right mi sedation septic shock shock STEMI Updated 2020