It’s easier to remember antibiotics that don’t need renal adjustment than antibiotics that do. Certain antibiotics ROMANCCED the kidneys.
- Rifampin
- Oxacillin
- Moxifloxacin
- Azithromycin
- Nafcillin
- Clindamycin
- Ceftriaxone
- Erythromycin
- Doxycycline
Antipseudomonals:
| IV : aminoglycodisdes pip/tazo (Zosyn) ticarcillin/clavulanic acid (Timentin) ceftazidime (Fortaz) cefepine (Maxipime) imipenem/cilastin (Primaxin) meropenem (Merem) doripenem (Dorax) ciprofloxacin (Cipro) colistin (Nebuliner) | PO: norfloxacin ofloxinc ciprofloxacin (best) levofloxin |
Carbapenems except Ertapenem – ErTapenam has a tail, so NO APES (aactinobacteria psuedomonas, enterococcus) [monkeys have tails, apes don’t]
“TCP” extended-spectrum penicillins (“Taking Care of Pseudomonas): ticarcillin, carbenicillin (not used much anymore), piperacillin
All flourquinoloens except moxifloxaxin are antipesunomonal. carbapenems except ertapenem, cefTAZidime and cefepime
MRSA Treatment:
| IV vancomycin (Vancocin) telavancin (Vibativ) daptomycin (Cubicin) linezolid (Zyvox) quinupristin (Syndercid) tigecycline (Tygacil) ceftaroline (Teflaro) | PO minocycline doxycycline Bactrim clindamycin linezolid tedizolid |
Fluoroquinolones impede neurotransmissin and have a direct toxic effect on the acetylecholine receptor