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Informatics in Pharmacy

Seizure Medication Table

August 13, 2018 By Dr. G, PharmD

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Table: 1 – first line drug, 2 – second line drug, 3 – some effect, 4 – adjunctive therapy, 5 – used only when benefits outweigh risks

DrugFocalTonic-ClonicAbsenceAtypical AbsenceAtonicMyoclonicInfantile SpasmsStatus EpilepticusLennox Gastaut
Acetazolamide4433     
Brivaracetam3        
Carbamazepine11  44   
Clobazam     3  1
Clonazepam3322122 1
Corticotropin      1  
Diazepam   4 4412
Eslicarbazepine4        
Ethosuximide  11 4   
Ezogabine4        
Felbamate555  5  5
Gabapentin12       
Lacosamide1      3 
Lamotrigine112433  1
Levetiracetam1    3 3 
Lorazepam3333 3 1 
Oxcarbazepine11  33   
Perampanel4        
Phenobarbital22   3 2 
Phenytoin22   3 1 
Pregabalin4        
Primidone222      
Rufinamide433 3   1
Tiagabine4   44   
Topiramate113 31   
Valproic Acid21111112 
Vigabatrin55    5  
Zonisamide133  4   
          

Here’s a chart from another reference, but I didn’t write it down:

Drugs and states that can induce seizures:

  • tramadol
  • fluoroquinolones
  • bupropion
  • imipenem/cilastatin
  • benzos when in withdrawal
  • alcohol withdrawal
  • hyponatremia
  • hypernatremia
  • hypercalcemia

Filed Under: Neurology

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acid base acidosis acute coronary syndrome alkalosis analgesics anaphylaxis aortic dissection arrhythmia bcps Beta-Blockers biostatistics blood pressure cardiac markers CHA2DS2-VasC cocaine COVID-19 diabetes diabetes inspidius heart failure Heparin hypersensitivity hypertension hypovolemic shock intubation ionotropes journal club lipids LMWH medication safety morphine conversions myocardial infarction needs work NOAC NSTEMI obstructive shock pharmacoeconomics pheochromocytoma pressors reference materials right mi sedation septic shock shock STEMI Updated 2020