This may look better in PDF Form. I have a whole section on resistance too. *These are basics, it’s a little more complicated in some cases.Grey is degraded, lighter grey is possible.
Guideline Materials and Tips
Agents and Monitoring
Parenteral Antimicrobial Agent Common Adult Parenteral Doses Monitoring/Unusual Adverse Effects PK/PD Elimination T 1/2 Action Cidal/Static(may not be clinically relevant) Anti-staphylococcal Agents (*MRSA) Nafcillin 1 to 2 g every 4 to 6h Nafcillin is an inducer of the cytochrome P450 3A4, Periodic CBC, urinalysis, BUN, SCr, AST and ALT, can cause mild hypokalemia T>MIC Billary […]
R Cheat Sheet for Biostats
R provides a wide array of functions to help you with statistical analysis with R—from simple statistics to complex analyses. Several statistical functions are built into R and R packages. R statistical functions fall into several categories including central tendency and variability, relative standing, t-tests, analysis of variance and regression analysis. Base R statistical functions for […]
Basic Biostatistics
If you need to brush up on biostatistics, I recommend you buy the little biostatistics book ACCP offers (it’s cheap and it has some good practice problems in it). This is also a really good study guide and here’s a really, really simple sheet. I have more topics in biostatistics (including the “which statistical test to pick” […]
Sexually Transmitted Infections
The CDC is the best place to check for updated STI guidelines and resistance patterns. Chlamydia: Doxycycline 100 mg orally 2 times/day for 7 days (preferred) Azithromycin 1g 1 time dose (can use in pregnancy) Levofloxacin 500 mg orally once daily for 7 days Alt in preg: Amoxicillin 500 mg orally 3 times/day for 7 days […]
Urinary Tract Infections
Please note that the current UTI guidelines don’t really meet practice. IDSA is due with new guidelines and a preview was presented at ID week in 2023/ECCMID 2024. It will change the definition of complicated UTIs to include pyelonephritis, catheter-associated UTI (CAUTI), UTI with fever or other evidence of systemic or upper tract infection and […]
Pneumonia
Community-Acquired Pneumonia (CAP) October 2019 IDSA CAP Adult Guidelines / CHEST CAP in Immunocompromised Patients / IDSA CAP in Kids Guidelines CAP is defined as pneumonia with an onset outside of the hospital setting or < 48 hours after hospital admission. Mortality ranges from < 1% to 50% depending on severity of illness. It is […]
Endocarditis Guideline Review
Causes: Bacterial infection is the most common cause of endocarditis, specifically viridans group strep, Staphylococcus aureus, HAECK group organisms (Haemophilus species, Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella kingae), or Enterococcus. Endocarditis can also be caused by fungi, such as Candida. Some weird fastidious bacteria show up too, like Bartonella, Brucella, Coxiella burnetii (causes […]
Sinus Troubles: When Should I See My Doctor
We’ve all had sinus troubles before and it’s sometimes hard to tell if it’s a bacterial infection, a virus, or allergies. Your physician probably even has a hard time. Here are some tips on when to see your physician, and when you should visit your local pharmacy for some home remedies. Viral Sinusitis If you’ve […]
Common Pharmacogenomic SNPs and Interactions
UM = ultrarapid metabolizer, EM = extensive metabolizer, IM = intermediate metabolizer, PM = poor metabolizer Drug SNP Types Effect Race Misc Ivacaftor CFTR amitriptyline CYP 2C19 UM (R), EM, IM, PM PM = increased conc, side effects, UM = decreased concen PM =Common in Asians UM=Common in Caucasions […]